1037 FACTORS DETERMINING THE CELLULAR UPTAKE OF BILIRUBIN
نویسندگان
چکیده
منابع مشابه
Factors determining uptake of diabetic retinopathy screening in Oxfordshire
AIMS To investigate variables at the demographic and primary care practice levels that influence the uptake of diabetic retinopathy screening. METHODS Data were extracted from the management software of one screening programme for 21 797 people registered with 79 general practices. Uptake was examined by gender, age group, modality of screening (mobile unit at general practice versus high-str...
متن کاملKinetics of hepatic uptake of unconjugated bilirubin.
1. The uptake of bilirubin was studied in the perfused rat liver by a multiple-indicator dilution technique employing the three-compartment model of Goresky. 2. The kinetics of hepatic bilirubin uptake could be described by the Michaelis-Menten equation. 3. The maximal uptake velocity (V max.) and the apparent half-saturation constant (Km) were 4-4 +/- 0-5 nmol s-1 g-1 of liver and 58 +/- 16 nm...
متن کاملInfluence of albumin on the hepatic uptake of unconjugated bilirubin.
1. The initial distiibution volumes of [3H]bilirubin in six adult subjects were equivalent to those of "I-labelled albumin following simultaneous intravenous injection of both compounds. However, the initial rate of loss of [3H]bilirubin from plasma was seven to thirty times faster than that of 1311-labelled albumin. 2. In vitro uptake of [3H]bilirubin by Gunn rat liver slices occurred at a rat...
متن کاملDmd064485 1037..1044
Since its identification in 2000, sulfotransferase (SULT) 4A1 has presented an enigma to the field of cytosolic SULT biology. SULT4A1 is exclusively expressed in neural tissue, is highly conserved, and has been identified in every vertebrate studied to date. Despite this singular level of conservation, no substrate or function for SULT4A1 has been identified. Previous studies demonstrated that ...
متن کاملZnO nanofluids for the improved cytotoxicity and cellular uptake of doxorubicin
Objective(s): Combination anticancer therapy holds promise for improving the therapeutic efficacy of chemotherapy drugs such as doxorubicin (DOX) as well as decreasing their dose-limiting side effects. Overcoming the side effects of doxorubicin (DOX) is a major challenge to the effective treatment of cancer. Zinc oxide nanoparticles (ZnO NPs) are emerging as potent tools for a wide variety of b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Research
سال: 1978
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197804001-01043